Amygdalin / Vitamin B17 CAS: 29883-15-6 | Molecular Formula: C₂₀H₂₇NO₁₁ | MW: 457.43

Purity: ≥98% (HPLC) | MOQ: 1 kg | Supply Capacity: 500 kg/month | Lead Time: 10–20 Days

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Amygdalin is a naturally occurring cyanogenic glycoside found in the seeds of Rosaceae plants — primarily bitter apricot kernels (Prunus armeniaca), bitter almonds, peach seeds, and apple seeds. With a 4,000-year history in traditional medicine, amygdalin remains an important active pharmaceutical ingredient for respiratory formulations in Traditional Chinese Medicine (TCM) and continues to be studied for its pharmacological properties.

Chemical Identity

Grade A — Pharmaceutical Grade (API for TCM Formulations)

Parameter	Specification
Purity (HPLC)	≥98.0%
Single Impurity	≤0.5%
Total Impurities	≤1.0%
Appearance	White to off-white crystalline powder
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	Pb < 2 ppm, As < 1 ppm, Hg < 0.2 ppm, Cd < 0.3 ppm
Residual HCN	<10 ppm (critical safety parameter)
Microbial	Total plate count < 100 CFU/g; E. coli, Salmonella absent
Specific Rotation	[α]D²⁰ = –38.5° to –42°
Standard	Chinese Pharmacopoeia (ChP) / LS/T 6151-2024
Packaging	100 g / 500 g / 1 kg aluminum-foil sealed bags, double PE inner, in amber glass bottles
Shelf Life	24 months (sealed, 2–10°C, protected from light and moisture)

Parameter	Detail
Chemical Name	(R)-Mandelonitrile β-D-gentiobioside
Common Names	Amygdalin, 苦杏仁苷, 扁桃苷, 苦杏仁甙, Vitamin B17, Laetrile
CAS Number	29883-15-6
Molecular Formula	C₂₀H₂₇NO₁₁
Molecular Weight	457.43
PubChem CID	6187
Chemical Class	Cyanogenic glycoside (cyanohydrin β-glycoside)
Structure	Gentiobiose (disaccharide) + (R)-mandelonitrile aglycone
Appearance	White to off-white crystalline powder
Melting Point	223–226°C (anhydrous); 200°C (trihydrate)
Specific Rotation	[α]D²⁰ = –38.5° to –42° (c=2, H₂O)
Solubility	Freely soluble in boiling water; slightly soluble in cold water and ethanol; insoluble in ether and chloroform
Plant Source	Semen Armeniacae Amarum (苦杏仁) — seeds of Prunus armeniaca L.
Natural Content	~3% in bitter apricot kernels; 0.05–3% in related Rosaceae seeds